Furthermore, it’s likely that the suggested doses for kudzu root will vary depending on the manufacturer and the type of supplement you may be considering. There isn’t much kudzu to stop drinking scientific evidence available on the dosing for kudzu root as a supplement. Kudzu root may increase the risk of liver injury or interact with certain medications, like birth control. Anecdotal sources say it may also be harmful to take with medications for diabetes or blood clotting. It’s important to note that this is a case study, so it can’t prove kudzu root caused this liver injury.

Anti-diabetic potential of Pueraria lobata root extract through promoting insulin signaling by PTP1B inhibition

• However, this effect by daidzin is not like a classical ALDH-2 inhibitor because it does not also inhibit the cytosolic form, of liver ALDH-1, which is a very efficient catalyst of acetaldehyde oxidation.
• It works by modulating glutamate transmission and acting as an NMDA receptor antagonist.
• The reduction in drinking was evident rather quickly as it was apparent for the second through sixth beers and no kudzu-treated participant drank five or six beers, which suggests that binge drinking was curtailed.
• For those seeking help with alcohol addiction, valuable resources are available online.
• In fact Keung et al. 5 demonstrated a direct correlation between ALDH-2 inhibition and ethanol intake suppression and raise the possibility that daidzin may in fact suppress ethanol intake of golden hamsters by inhibiting ALDH-2.

The correlational analysis of absolute amount of alcohol consumed and breath alcohol levels in this study indicates that the physiological effects and the rate of elimination of ingested alcohol are not altered by kudzu administration. This was demonstrated in our previous study (Penetar et al., 2011) where pharmacokinetic parameters such as peak concentration and elimination time were not affected by kudzu. In that study, however, we did find evidence of an initial more rapid rise in blood alcohol levels in kudzu-treated individuals, suggesting that isoflavones may alter bioavailability of alcohol to the brain during the ascending alcohol absorption phase.

What Happens If You Drink Alcohol While Taking Kudzu?

It’s important to note that the standardized content of the important active compounds, primarily puerarin, varies among different products. The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature https://ecosoberhouse.com/ of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.

The big experiment: could I lose fat just by changing my meal times?

• Several of the subjects had been drinking for many years and often drank to or past the point of inebriation.
• A major limitation to this pilot is the small number of subjects evaluated and as such we caution any definitive interpretation of these interesting results.
• Over time, if you regularly drink, you’re likely to develop a tolerance and need more alcohol to achieve the desired effects.
• Subjects were all Caucasian, lower to middle income, residing in a small Midwestern town.

The root of the Kudzu plant has been used for centuries in Chinese medicine to treat a variety of ailments, including alcoholism. The root contains isoflavones, a compound that has been shown to reduce alcohol consumption in rats. Kudzu root extract is now widely used in the United States as a natural remedy for alcoholism. While kudzu can help you cut back on your drinking, if you believe that you’re alcohol-dependent or you’re struggling with addiction, you should talk to a professional. Kudzu won’t help alcohol withdrawal symptoms, which can ultimately be deadly. It’s also not a replacement for professional addiction treatment, which includes behavioral therapies and other approaches.

If you experience any adverse reactions while using kudzu, consult your healthcare provider promptly. Jukić, Tomislav; Rojc, Bojan; Boben-Bardutzky, Darja; et al. “The use of a food supplementation with D… withdrawal symptoms.” Collegium Antropologicum, December 2011. Although many different B vitamins can be impacted by drinking, one of the most dangerous B-vitamin deficiencies is thiamine or vitamin B1. Lack of vitamin B1 can cause a life-threatening condition called Wernicke-Korsakoff syndrome. For this reason, those who struggle with alcohol are often told to take vitamin B1. There is also good evidence that drinking clear spirits reduces the severity of hangovers.